Publications
Sanganalmath SK, Dubey S, Veeranki S, Narisetty K, Krishnamurthy P. The interplay of inflammation, exosomes and Ca2+ dynamics in diabetic cardiomyopathy. Cardiovasc Diabetol. 2023 Feb 20;22(1):37. doi: 10.1186/s12933-023-01755-1. PMID: 36804872.
Dubey S, Dubey PK, Umeshappa CS, Ghebre YT, Krishnamurthy P. Inhibition of RUNX1 blocks the differentiation of lung fibroblasts to myofibroblasts. J Cell Physiol. 2022 Jan 19;. doi: 10.1002/jcp.30684. PubMed PMID: 35048404.
Patil M, Saheera S, Dubey PK, Kahn-Krell A, Kumar Govindappa P, Singh S, Tousif S, Zhang Q, Lal H, Zhang J, Qin G, Krishnamurthy P. Novel Mechanisms of Exosome-Mediated Phagocytosis of Dead Cells in Injured Heart. Circ Res. 2021 Nov 12;129(11):1006-1020. doi: 10.1161/CIRCRESAHA.120.317900. Epub 2021 Oct 8. PubMed PMID: 34623174; PubMed Central PMCID: PMC8595793.
Singh S, Henderson J, Patil M, Dubey PK, Dubey S, Kannappan R, Zhang J, Krishnamurthy P. MicroRNA-181c-5p modulates phagocytosis efficiency in bone marrow-derived macrophages. Inflamm Res. 2022 Jan 12;. doi: 10.1007/s00011-022-01539-5. [Epub ahead of print] PubMed PMID: 35020000.
Dubey PK, Patil M, Singh S, Dubey S, Ahuja P, Verma SK, Krishnamurthy P. Increased m6A-RNA methylation and FTO suppression is associated with myocardial inflammation and dysfunction during endotoxemia in mice. Mol Cell Biochem. 2022 Jan;477(1):129-141. doi: 10.1007/s11010-021-04267-2. Epub 2021 Sep 28. PubMed PMID: 34581943; PubMed Central PMCID: PMC8758538.
Zhou J, Singh N, Monnier C, Marszalec W, Gao L, Jin J, Frisk M, Louch WE, Verma S, Krishnamurthy P, Nico E, Mulla M, Aistrup GL, Kishore R, Wasserstrom JA. Phosphatidylinositol-4,5-Bisphosphate Binding to Amphiphysin-II Modulates T-Tubule Remodeling: Implications for Heart Failure. Front Physiol. 2021;12:782767. doi: 10.3389/fphys.2021.782767. eCollection 2021. PubMed PMID: 35002765; PubMed Central PMCID: PMC8733645.
Sunny S, Challa AK, Qiao A, Jyothidasan A, Krishnamurthy P, Ramamurthy MT, Crossman DK, Pogwizd S, Cinghu S, Rajasekaran NS. Transcriptional Regulation of Structural and Functional Adaptations in a Developing Adulthood Myocardium. Cardiol Cardiovasc Med. 2021;5(5):454-470. doi: 10.26502/fccm.92920215. Epub 2021 Sep 7. PubMed PMID: 34497977; PubMed Central PMCID: PMC8423094.
Henderson J, Dubey PK, Patil M, Singh S, Dubey S, Namakkal Soorappan R, Kannappan R, Sethu P, Qin G, Zhang J, Krishnamurthy P. microRNA-377 Signaling Modulates Anticancer Drug-Induced Cardiotoxicity in Mice. Front Cardiovasc Med. 2021;8:737826. doi: 10.3389/fcvm.2021.737826. eCollection 2021. PubMed PMID: 34485421; PubMed Central PMCID: PMC8415717.
Patil M, Singh S, Henderson J, Krishnamurthy P. Mechanisms of COVID-19-induced cardiovascular disease: Is sepsis or exosome the missing link?. J Cell Physiol. 2021 May;236(5):3366-3382. doi: 10.1002/jcp.30109. Epub 2020 Oct 20. Review. PubMed PMID: 33078408; PubMed Central PMCID: PMC7920909.
Luong H, Singh S, Patil M, Krishnamurthy P. Cardiac glycosaminoglycans and structural alterations during chronic stress-induced depression-like behavior in mice. Am J Physiol Heart Circ Physiol. 2021 May 1;320(5):H2044-H2057. doi: 10.1152/ajpheart.00635.2020. Epub 2021 Apr 9. PubMed PMID: 33834865; PubMed Central PMCID: PMC8163649.
Gao L, Wang L, Wei Y, Krishnamurthy P, Walcott GP, Menasché P, Zhang J. Exosomes secreted by hiPSC-derived cardiac cells improve recovery from myocardial infarction in swine. Sci Transl Med. 2020 Sep 16;12(561). doi: 10.1126/scitranslmed.aay1318. PubMed PMID: 32938792.
Gupta R, Liu L, Zhang X, Fan X, Krishnamurthy P, Verma S, Tongers J, Misener S, Ashcherkin N, Sun H, Tian J, Kishore R. IL-10 provides cardioprotection in diabetic myocardial infarction via upregulation of Heme clearance pathways. JCI Insight. 2020 Sep 3;5(17). doi: 10.1172/jci.insight.133050. PubMed PMID: 32879134; PubMed Central PMCID: PMC7526458.
Saheera S, Potnuri AG, Krishnamurthy P. Nano-Vesicle (Mis)Communication in Senescence-Related Pathologies. Cells. 2020 Aug 26;9(9). doi: 10.3390/cells9091974. Review. PubMed PMID: 32859053; PubMed Central PMCID: PMC7564330.
Fan C, Oduk Y, Zhao M, Lou X, Tang Y, Pretorius D, Valarmathi MT, Walcott GP, Yang J, Menasche P, Krishnamurthy P, Zhu W, Zhang J. Myocardial protection by nanomaterials formulated with CHIR99021 and FGF1. JCI Insight. 2020 Jun 18;5(12). doi: 10.1172/jci.insight.132796. PubMed PMID: 32453715; PubMed Central PMCID: PMC7406256.
Sreejit G, Flynn MC, Patil M, Krishnamurthy P, Murphy AJ, Nagareddy PR. S100 family proteins in inflammation and beyond. Adv Clin Chem. 2020;98:173-231. doi: 10.1016/bs.acc.2020.02.006. Epub 2020 Apr 17. Review. PubMed PMID: 32564786.
Miller JM, Mardhekar NM, Pretorius D, Krishnamurthy P, Rajasekaran NS, Zhang J, Kannappan R. DNA damage-free iPS cells exhibit potential to yield competent cardiomyocytes. Am J Physiol Heart Circ Physiol. 2020 Apr 1;318(4):H801-H815. doi: 10.1152/ajpheart.00658.2019. Epub 2020 Feb 14. PubMed PMID: 32057252; PubMed Central PMCID: PMC7276931.
Govindappa PK, Patil M, Garikipati VNS, Verma SK, Saheera S, Narasimhan G, Zhu W, Kishore R, Zhang J, Krishnamurthy P. Targeting exosome-associated human antigen R attenuates fibrosis and inflammation in diabetic heart. FASEB J. 2020 Feb;34(2):2238-2251. doi: 10.1096/fj.201901995R. Epub 2019 Dec 16. PubMed PMID: 31907992; PubMed Central PMCID: PMC8286699.
Saheera S, Krishnamurthy P. Cardiovascular Changes Associated with Hypertensive Heart Disease and Aging. Cell Transplant. 2020 Jan-Dec;29:963689720920830. doi: 10.1177/0963689720920830. Review. PubMed PMID: 32393064; PubMed Central PMCID: PMC7586256.
Patil M, Henderson J, Luong H, Annamalai D, Sreejit G, Krishnamurthy P. The Art of Intercellular Wireless Communications: Exosomes in Heart Disease and Therapy. Front Cell Dev Biol. 2019;7:315. doi: 10.3389/fcell.2019.00315. eCollection 2019. Review. PubMed PMID: 31850349; PubMed Central PMCID: PMC6902075.
Fan C, Fast VG, Tang Y, Zhao M, Turner JF, Krishnamurthy P, Rogers JM, Valarmathi MT, Yang J, Zhu W, Zhang J. Cardiomyocytes from CCND2-overexpressing human induced-pluripotent stem cells repopulate the myocardial scar in mice: A 6-month study. J Mol Cell Cardiol. 2019 Dec;137:25-33. doi: 10.1016/j.yjmcc.2019.09.011. Epub 2019 Oct 17. PubMed PMID: 31629738; PubMed Central PMCID: PMC7346870.
Han S, Xu S, Zhou J, Qiao A, Boriboun C, Ma W, Li H, Biyashev D, Yang L, Zhang E, Liu Q, Jiang S, Zhao TC, Krishnamurthy P, Zhang C, Richard S, Qiu H, Zhang J, Qin G. Sam68 impedes the recovery of arterial injury by augmenting inflammatory response. J Mol Cell Cardiol. 2019 Dec;137:82-92. doi: 10.1016/j.yjmcc.2019.10.003. Epub 2019 Oct 19. PubMed PMID: 31639388; PubMed Central PMCID: PMC6889069.
Narasimhan G, Henderson J, Luong HT, Rajasekaran NS, Qin G, Zhang J, Krishnamurthy P. OBG-like ATPase 1 inhibition attenuates angiotensin II-induced hypertrophic response in human ventricular myocytes via GSK-3beta/beta-catenin signalling. Clin Exp Pharmacol Physiol. 2019 Aug;46(8):743-751. doi: 10.1111/1440-1681.13101. Epub 2019 May 23. PubMed PMID: 31063653; PubMed Central PMCID: PMC6650359.
Shanmugam G, Challa AK, Devarajan A, Athmanathan B, Litovsky SH, Krishnamurthy P, Davidson CJ, Rajasekaran NS. Exercise Mediated Nrf2 Signaling Protects the Myocardium From Isoproterenol-Induced Pathological Remodeling. Front Cardiovasc Med. 2019;6:68. doi: 10.3389/fcvm.2019.00068. eCollection 2019. PubMed PMID: 31245386; PubMed Central PMCID: PMC6563599.
Berry JL, Zhu W, Tang YL, Krishnamurthy P, Ge Y, Cooke JP, Chen Y, Garry DJ, Yang HT, Rajasekaran NS, Koch WJ, Li S, Domae K, Qin G, Cheng K, Kamp TJ, Ye L, Hu S, Ogle BM, Rogers JM, Abel ED, Davis ME, Prabhu SD, Liao R, Pu WT, Wang Y, Ping P, Bursac N, Vunjak-Novakovic G, Wu JC, Bolli R, Menasché P, Zhang J. Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure. Circ Res. 2019 Jan 4;124(1):161-169. doi: 10.1161/CIRCRESAHA.118.314216. PubMed PMID: 30605412; PubMed Central PMCID: PMC6350935.
Verma SK, Garikipati VNS, Krishnamurthy P, Schumacher SM, Grisanti LA, Cimini M, Cheng Z, Khan M, Yue Y, Benedict C, Truongcao MM, Rabinowitz JE, Goukassian DA, Tilley D, Koch WJ, Kishore R. Interleukin-10 Inhibits Bone Marrow Fibroblast Progenitor Cell-Mediated Cardiac Fibrosis in Pressure-Overloaded Myocardium. Circulation. 2017 Sep 5;136(10):940-953. doi: 10.1161/CIRCULATIONAHA.117.027889. Epub 2017 Jun 30. PubMed PMID: 28667100; PubMed Central PMCID: PMC5736130.
Garikipati VNS, Verma SK, Jolardarashi D, Cheng Z, Ibetti J, Cimini M, Tang Y, Khan M, Yue Y, Benedict C, Nickoloff E, Truongcao MM, Gao E, Krishnamurthy P, Goukassian DA, Koch WJ, Kishore R. Therapeutic inhibition of miR-375 attenuates post-myocardial infarction inflammatory response and left ventricular dysfunction via PDK-1-AKT signalling axis. Cardiovasc Res. 2017 Jul 1;113(8):938-949. doi: 10.1093/cvr/cvx052. PubMed PMID: 28371849.
Ghebre YT, Yakubov E, Wong WT, Krishnamurthy P, Sayed N, Sikora AG, Bonnen MD. Vascular Aging: Implications for Cardiovascular Disease and Therapy. Transl Med (Sunnyvale). 2016 Dec;6(4). doi: 10.4172/2161-1025.1000183. Epub 2016 Aug 30. PubMed PMID: 28932625; PubMed Central PMCID: PMC5602592.
Suresh Babu S, Thandavarayan RA, Joladarashi D, Jeyabal P, Krishnamurthy S, Bhimaraj A, Youker KA, Krishnamurthy P. MicroRNA-126 overexpression rescues diabetes-induced impairment in efferocytosis of apoptotic cardiomyocytes. Sci Rep. 2016 Nov 9;6:36207. doi: 10.1038/srep36207. PubMed PMID: 27827458; PubMed Central PMCID: PMC5101812.
Sreedhar R, Giridharan VV, Arumugam S, Karuppagounder V, Palaniyandi SS, Krishnamurthy P, Quevedo J, Watanabe K, Konishi T, Thandavarayan RA. Role of MAPK-mediated endoplasmic reticulum stress signaling in the heart during aging in senescence-accelerated prone mice. Biofactors. 2016 Jul 8;42(4):368-75. doi: 10.1002/biof.1280. Epub 2016 Apr 18. PubMed PMID: 27087487.
Giridharan VV, Quevedo J, Krishnamurthy P, Thandavarayan RA. Editorial Commentary: miRNA a tiny genetic tool: Key to the puzzle of cardiovascular disease. Trends Cardiovasc Med. 2016 Jul;26(5):420-2. doi: 10.1016/j.tcm.2016.03.007. Epub 2016 Mar 15. PubMed PMID: 27079892.
Karuppagounder V, Arumugam S, Thandavarayan RA, Sreedhar R, Giridharan VV, Pitchaimani V, Afrin R, Harima M, Krishnamurthy P, Suzuki K, Nakamura M, Ueno K, Watanabe K. Naringenin ameliorates skin inflammation and accelerates phenotypic reprogramming from M1 to M2 macrophage polarization in atopic dermatitis NC/Nga mouse model. Exp Dermatol. 2016 May;25(5):404-7. doi: 10.1111/exd.12962. PubMed PMID: 26836240.
Karuppagounder V, Giridharan VV, Arumugam S, Sreedhar R, Palaniyandi SS, Krishnamurthy P, Quevedo J, Watanabe K, Konishi T, Thandavarayan RA. Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice. PLoS One. 2016;11(4):e0152922. doi: 10.1371/journal.pone.0152922. eCollection 2016. PubMed PMID: 27070323; PubMed Central PMCID: PMC4829159.
Munukutla S, Pan G, Deshpande M, Thandavarayan RA, Krishnamurthy P, Palaniyandi SS. Alcohol Toxicity in Diabetes and Its Complications: A Double Trouble?. Alcohol Clin Exp Res. 2016 Apr;40(4):686-97. doi: 10.1111/acer.13008. Epub 2016 Mar 25. Review. PubMed PMID: 27013182.
Arumugam S, Sreedhar R, Thandavarayan RA, Karuppagounder V, Krishnamurthy P, Suzuki K, Nakamura M, Watanabe K. Angiotensin receptor blockers: Focus on cardiac and renal injury. Trends Cardiovasc Med. 2016 Apr;26(3):221-8. doi: 10.1016/j.tcm.2015.06.004. Epub 2015 Jun 15. Review. PubMed PMID: 26169314.
Jeyabal P, Thandavarayan RA, Joladarashi D, Suresh Babu S, Krishnamurthy S, Bhimaraj A, Youker KA, Kishore R, Krishnamurthy P. MicroRNA-9 inhibits hyperglycemia-induced pyroptosis in human ventricular cardiomyocytes by targeting ELAVL1. Biochem Biophys Res Commun. 2016 Mar 18;471(4):423-9. doi: 10.1016/j.bbrc.2016.02.065. Epub 2016 Feb 17. PubMed PMID: 26898797; PubMed Central PMCID: PMC4818978.
Verma SK, Garikipati VN, Krishnamurthy P, Khan M, Thorne T, Qin G, Losordo DW, Kishore R. IL-10 Accelerates Re-Endothelialization and Inhibits Post-Injury Intimal Hyperplasia following Carotid Artery Denudation. PLoS One. 2016;11(1):e0147615. doi: 10.1371/journal.pone.0147615. eCollection 2016. PubMed PMID: 26808574; PubMed Central PMCID: PMC4725953.
Sreedhar R, Arumugam S, Thandavarayan RA, Giridharan VV, Karuppagounder V, Pitchaimani V, Afrin R, Harima M, Nakamura M, Suzuki K, Gurusamy N, Krishnamurthy P, Watanabe K. Depletion of cardiac 14-3-3η protein adversely influences pathologic cardiac remodeling during myocardial infarction after coronary artery ligation in mice. Int J Cardiol. 2016 Jan 1;202:146-53. doi: 10.1016/j.ijcard.2015.08.142. Epub 2015 Aug 24. PubMed PMID: 26386943.
Garikipati VN, Krishnamurthy P, Verma SK, Khan M, Abramova T, Mackie AR, Qin G, Benedict C, Nickoloff E, Johnson J, Gao E, Losordo DW, Houser SR, Koch WJ, Kishore R. Negative Regulation of miR-375 by Interleukin-10 Enhances Bone Marrow-Derived Progenitor Cell-Mediated Myocardial Repair and Function After Myocardial Infarction. Stem Cells. 2015 Dec;33(12):3519-29. doi: 10.1002/stem.2121. Epub 2015 Aug 25. PubMed PMID: 26235810; PubMed Central PMCID: PMC4713300.
Kishore R, Krishnamurthy P, Garikipati VN, Benedict C, Nickoloff E, Khan M, Johnson J, Gumpert AM, Koch WJ, Verma SK. Interleukin-10 inhibits chronic angiotensin II-induced pathological autophagy. J Mol Cell Cardiol. 2015 Dec;89(Pt B):203-13. doi: 10.1016/j.yjmcc.2015.11.004. Epub 2015 Nov 6. PubMed PMID: 26549357; PubMed Central PMCID: PMC4689660.
Joladarashi D, Garikipati VNS, Thandavarayan RA, Verma SK, Mackie AR, Khan M, Gumpert AM, Bhimaraj A, Youker KA, Uribe C, Suresh Babu S, Jeyabal P, Kishore R, Krishnamurthy P. Enhanced Cardiac Regenerative Ability of Stem Cells After Ischemia-Reperfusion Injury: Role of Human CD34+ Cells Deficient in MicroRNA-377. J Am Coll Cardiol. 2015 Nov 17;66(20):2214-2226. doi: 10.1016/j.jacc.2015.09.009. PubMed PMID: 26564600; PubMed Central PMCID: PMC4644493.
Giridharan VV, Thandavarayan RA, Arumugam S, Mizuno M, Nawa H, Suzuki K, Ko KM, Krishnamurthy P, Watanabe K, Konishi T. Schisandrin B Ameliorates ICV-Infused Amyloid β Induced Oxidative Stress and Neuronal Dysfunction through Inhibiting RAGE/NF-κB/MAPK and Up-Regulating HSP/Beclin Expression. PLoS One. 2015;10(11):e0142483. doi: 10.1371/journal.pone.0142483. eCollection 2015. PubMed PMID: 26556721; PubMed Central PMCID: PMC4640572.
Suresh Babu S, Joladarashi D, Jeyabal P, Thandavarayan RA, Krishnamurthy P. RNA-stabilizing proteins as molecular targets in cardiovascular pathologies. Trends Cardiovasc Med. 2015 Nov;25(8):676-83. doi: 10.1016/j.tcm.2015.02.006. Epub 2015 Feb 20. Review. PubMed PMID: 25801788; PubMed Central PMCID: PMC4545469.
Jeyabal P, Thandavarayan RA, Babu SS, Krishnamurthy P. Enhancer-associated long noncoding RNAs: A novel frontier with new perception in cardiac regeneration. Trends Cardiovasc Med. 2015 Oct;25(7):603-5. doi: 10.1016/j.tcm.2015.02.010. Epub 2015 Feb 23. PubMed PMID: 25812420; PubMed Central PMCID: PMC4546919.
Thandavarayan RA, Garikipati VN, Joladarashi D, Suresh Babu S, Jeyabal P, Verma SK, Mackie AR, Khan M, Arumugam S, Watanabe K, Kishore R, Krishnamurthy P. Sirtuin-6 deficiency exacerbates diabetes-induced impairment of wound healing. Exp Dermatol. 2015 Oct;24(10):773-8. doi: 10.1111/exd.12762. Epub 2015 Aug 18. PubMed PMID: 26010430; PubMed Central PMCID: PMC4583793.
Khan M, Nickoloff E, Abramova T, Johnson J, Verma SK, Krishnamurthy P, Mackie AR, Vaughan E, Garikipati VN, Benedict C, Ramirez V, Lambers E, Ito A, Gao E, Misener S, Luongo T, Elrod J, Qin G, Houser SR, Koch WJ, Kishore R. Embryonic stem cell-derived exosomes promote endogenous repair mechanisms and enhance cardiac function following myocardial infarction. Circ Res. 2015 Jun 19;117(1):52-64. doi: 10.1161/CIRCRESAHA.117.305990. Epub 2015 Apr 22. PubMed PMID: 25904597; PubMed Central PMCID: PMC4482130.
Thandavarayan RA, Giridharan VV, Arumugam S, Suzuki K, Ko KM, Krishnamurthy P, Watanabe K, Konishi T. Schisandrin B prevents doxorubicin induced cardiac dysfunction by modulation of DNA damage, oxidative stress and inflammation through inhibition of MAPK/p53 signaling. PLoS One. 2015;10(3):e0119214. doi: 10.1371/journal.pone.0119214. eCollection 2015. PubMed PMID: 25742619; PubMed Central PMCID: PMC4351084.
Joladarashi D, Thandavarayan RA, Babu SS, Krishnamurthy P. Small engine, big power: microRNAs as regulators of cardiac diseases and regeneration. Int J Mol Sci. 2014 Sep 9;15(9):15891-911. doi: 10.3390/ijms150915891. Review. PubMed PMID: 25207600; PubMed Central PMCID: PMC4200826.
Mackie AR, Krishnamurthy P, Verma SK, Thorne T, Ramirez V, Qin G, Abramova T, Hamada H, Losordo DW, Kishore R. Alcohol consumption negates estrogen-mediated myocardial repair in ovariectomized mice by inhibiting endothelial progenitor cell mobilization and function. J Biol Chem. 2013 Jun 21;288(25):18022-34. doi: 10.1074/jbc.M113.468009. Epub 2013 May 3. PubMed PMID: 23645678; PubMed Central PMCID: PMC3689947.
Kishore R, Verma SK, Mackie AR, Vaughan EE, Abramova TV, Aiko I, Krishnamurthy P. Bone marrow progenitor cell therapy-mediated paracrine regulation of cardiac miRNA-155 modulates fibrotic response in diabetic hearts. PLoS One. 2013;8(4):e60161. doi: 10.1371/journal.pone.0060161. Epub 2013 Apr 1. PubMed PMID: 23560074; PubMed Central PMCID: PMC3613379.
Hoxha E, Lambers E, Xie H, De Andrade A, Krishnamurthy P, Wasserstrom JA, Ramirez V, Thal M, Verma SK, Soares MB, Kishore R. Histone deacetylase 1 deficiency impairs differentiation and electrophysiological properties of cardiomyocytes derived from induced pluripotent cells. Stem Cells. 2012 Nov;30(11):2412-22. doi: 10.1002/stem.1209. PubMed PMID: 22915496; PubMed Central PMCID: PMC3479375.
Hoxha E, Lambers E, Wasserstrom JA, Mackie A, Ramirez V, Abramova T, Verma SK, Krishnamurthy P, Kishore R. Elucidation of a novel pathway through which HDAC1 controls cardiomyocyte differentiation through expression of SOX-17 and BMP2. PLoS One. 2012;7(9):e45046. doi: 10.1371/journal.pone.0045046. Epub 2012 Sep 12. PubMed PMID: 22984607; PubMed Central PMCID: PMC3440419.
Verma SK, Krishnamurthy P, Barefield D, Singh N, Gupta R, Lambers E, Thal M, Mackie A, Hoxha E, Ramirez V, Qin G, Sadayappan S, Ghosh AK, Kishore R. Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB. Circulation. 2012 Jul 24;126(4):418-29. doi: 10.1161/CIRCULATIONAHA.112.112185. Epub 2012 Jun 15. PubMed PMID: 22705886; PubMed Central PMCID: PMC3422741.
Thal MA, Krishnamurthy P, Mackie AR, Hoxha E, Lambers E, Verma S, Ramirez V, Qin G, Losordo DW, Kishore R. Enhanced angiogenic and cardiomyocyte differentiation capacity of epigenetically reprogrammed mouse and human endothelial progenitor cells augments their efficacy for ischemic myocardial repair. Circ Res. 2012 Jul 6;111(2):180-90. doi: 10.1161/CIRCRESAHA.112.270462. Epub 2012 May 15. PubMed PMID: 22589372; PubMed Central PMCID: PMC3406600.
Krishnamurthy P, Thal M, Verma S, Hoxha E, Lambers E, Ramirez V, Qin G, Losordo D, Kishore R. Interleukin-10 deficiency impairs bone marrow-derived endothelial progenitor cell survival and function in ischemic myocardium. Circ Res. 2011 Nov 11;109(11):1280-9. doi: 10.1161/CIRCRESAHA.111.248369. Epub 2011 Sep 29. PubMed PMID: 21959218; PubMed Central PMCID: PMC3235675.
Krishnamurthy P, Lambers E, Verma S, Thorne T, Qin G, Losordo DW, Kishore R. Myocardial knockdown of mRNA-stabilizing protein HuR attenuates post-MI inflammatory response and left ventricular dysfunction in IL-10-null mice. FASEB J. 2010 Jul;24(7):2484-94. doi: 10.1096/fj.09-149815. Epub 2010 Mar 10. PubMed PMID: 20219984; PubMed Central PMCID: PMC2887267.
Kishore R, Krishnamurthy P, Losordo DW. Career moves: induced pluripotent cells from human aortic smooth muscle cells can efficiently redifferentiate into parental phenotype. Circ Res. 2010 Jan 8;106(1):7-9. doi: 10.1161/CIRCRESAHA.109.210351. PubMed PMID: 20056938; PubMed Central PMCID: PMC3132886.
Krishnamurthy P, Peterson JT, Subramanian V, Singh M, Singh K. Inhibition of matrix metalloproteinases improves left ventricular function in mice lacking osteopontin after myocardial infarction. Mol Cell Biochem. 2009 Feb;322(1-2):53-62. doi: 10.1007/s11010-008-9939-6. Epub 2008 Nov 1. PubMed PMID: 18979185; PubMed Central PMCID: PMC2711544.
Krishnamurthy P, Rajasingh J, Lambers E, Qin G, Losordo DW, Kishore R. IL-10 inhibits inflammation and attenuates left ventricular remodeling after myocardial infarction via activation of STAT3 and suppression of HuR. Circ Res. 2009 Jan 30;104(2):e9-18. doi: 10.1161/CIRCRESAHA.108.188243. Epub 2008 Dec 18. PubMed PMID: 19096025; PubMed Central PMCID: PMC2774810.
Rajasingh J, Lambers E, Hamada H, Bord E, Thorne T, Goukassian I, Krishnamurthy P, Rosen KM, Ahluwalia D, Zhu Y, Qin G, Losordo DW, Kishore R. Cell-free embryonic stem cell extract-mediated derivation of multipotent stem cells from NIH3T3 fibroblasts for functional and anatomical ischemic tissue repair. Circ Res. 2008 Jun 6;102(11):e107-17. doi: 10.1161/CIRCRESAHA.108.176115. Epub 2008 May 15. PubMed PMID: 18483406; PubMed Central PMCID: PMC2435186.
Krishnamurthy P, Subramanian V, Singh M, Singh K. Beta1 integrins modulate beta-adrenergic receptor-stimulated cardiac myocyte apoptosis and myocardial remodeling. Hypertension. 2007 Apr;49(4):865-72. doi: 10.1161/01.HYP.0000258703.36986.13. Epub 2007 Feb 5. PubMed PMID: 17283249.
Subramanian V, Krishnamurthy P, Singh K, Singh M. Lack of osteopontin improves cardiac function in streptozotocin-induced diabetic mice. Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H673-83. doi: 10.1152/ajpheart.00569.2006. Epub 2006 Sep 15. PubMed PMID: 16980342.
Menon B, Krishnamurthy P, Kaverina E, Johnson JN, Ross RS, Singh M, Singh K. Expression of the cytoplasmic domain of beta1 integrin induces apoptosis in adult rat ventricular myocytes (ARVM) via the involvement of caspase-8 and mitochondrial death pathway. Basic Res Cardiol. 2006 Nov;101(6):485-93. doi: 10.1007/s00395-006-0602-7. Epub 2006 Jun 16. PubMed PMID: 16783488.
Krishnamurthy P, Subramanian V, Singh M, Singh K. Deficiency of beta1 integrins results in increased myocardial dysfunction after myocardial infarction. Heart. 2006 Sep;92(9):1309-15. doi: 10.1136/hrt.2005.071001. Epub 2006 Mar 17. PubMed PMID: 16547211; PubMed Central PMCID: PMC1861145.
Shivachandra SB, Kumar AA, Singh SD, Shivakumar BM, Prasanna K. Pathogenicity of Pasteurella multocida A:1 in experimentally infected chickens and chicken embryos. Indian Journal of Animal Sciences. 2005 Apr;75(4):411-414.
Prasanna K, Paliwal OP, Verma JC. Correlation of clinicopathological and microbiological studies in experimental fowl typhoid and pullorum disease in chicken. Indian Journal of Animal Sciences. 2003 Jun;73(6):627-629.
Prasanna K, Paliwal OP, Kumar R, Tripathi BN. Immunocytochemical detection of Salmonella Gallinarum and Salmonella Pullorum in experimentally infected chickens. Indian Journal of Animal Sciences. 2002 Feb;72(2):113-116.